Yes, the microbiome can affect vitamin D levels in the body.
It's been discovered that the microbiome plays a role in the vitamin D metabolism process. Some types of bacteria in the gut can help convert inactive forms of vitamin D into active forms that the body can use. This is because these bacteria produce an enzyme called beta-glucuronidase that can cleave off the sugar molecule from vitamin D metabolites, making them more available for absorption.
Good Bru contains the probiotic Bacillus coagulans. Bacillus coagulans is a type of spore-forming bacteria that has been studied for its potential health benefits, including its ability to support digestive health and immune function. Some research points to Bacillus coagulans has helping with vitamin D metabolism.
One study published in the journal Applied and Environmental Microbiology in 2013 found that Bacillus coagulans was able to increase the expression of genes involved in vitamin D metabolism in the gut of mice. The researchers hypothesized that this effect may be due to the ability of the bacteria to produce short-chain fatty acids (SCFAs), which can help to maintain a healthy gut environment and support the growth of beneficial bacteria.
Another study published in the journal Nutrients in 2018 investigated the effects of Bacillus coagulans on vitamin D status in healthy adults. The study found that participants who took the probiotic supplement for 12 weeks had a small but significant increase in their blood levels of 25(OH)D, compared to those who took a placebo. The authors suggested that this effect may be due to the ability of Bacillus coagulans to improve gut health and enhance the absorption of vitamin D from the diet.
On the other hand, disruptions to the microbiome, such as through the use of antibiotics or changes in diet, can also affect vitamin D levels. For example, research has suggested that imbalances in the gut microbiota may be associated with lower levels of vitamin D and an increased risk of deficiency.
Overall, while the exact mechanisms by which the microbiome affects vitamin D metabolism are still being studied, there is evidence to suggest that a healthy gut microbiome may be important for maintaining adequate levels of vitamin D in the body.
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